Category: Cancer Detection and Tumor Markers
In what could be disappointing news for some individuals who have taken a cancer biomarker blood test that found lung tumors, a lung cancer drug that was in development by Astex Pharmaceuticals has been discontinued. The drug, amuvatinib, was shelved in light of its failure to display the desired effectiveness.
"We have decided to end the clinical development of amuvatinib, despite the favorable safety and preliminary clinical activity we observed in the first stage of this Phase 2 trial and in the earlier Phase 1b trial in combination platinum-etoposide based chemotherapy," said James S.J. Manuso, chairman and CEO of Astex Pharmaceuticals.
The chairman also stated that amuvatinib could possibly be licensed to other drug developers, if his company allows.
According to Reuters, the drug was shelved after failing to produce a 10 percent rate of reaction in lung cancer patients.
The National Center for Biotechnology Information notes that a positive result from a blood test for lung cancer could be linked to asbestos, heredity and living in an area with high levels of air pollution. However, smoking is by far the leading cause of lung cancer.
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