Accutane is a powerful drug that can be used to treat severe acne. It effectively clears up most cases of this skin condition, but some side effects are associated with the use of this medication. One of Accutane’s side effects is that it can cause lower testosterone levels for some people who take it.

Testosterone: The Male Hormone

Testosterone is an androgen. Androgens include hormones that play a crucial role in male development, such as testosterone, dihydrotestosterone (DHT), and others. Testosterone is the most important of these hormones because it has a powerful effect on male development and how they behave throughout their lives.

In women, testosterone is produced in small amounts by the ovaries and adrenal glands — but it plays only minor roles in female physiology compared to its role in men.

Research Shows That Accutane Can Lower Testosterone

Accutane, also known as isotretinoin, is a drug that is used to treat severe acne. It’s the most effective treatment for severe forms of acne and has been shown to clear up 80% of lesions in people with severe cystic acne.

Accutane can lower testosterone levels, which is precisely a way to combat the pathogenesis of acne (the origin of the condition). How much Accutane lowers testosterone depends on the person—some people may experience no change at all, while others may significantly drop their T-levels. Usually, however, this testosterone reduction will not permanently damage your hormonal system unless you develop more serious complications from your treatment. 

Unfortunately, it’s difficult to say exactly how much testosterone Accutane will lower for you. There is not much research on this issue. However, you can discuss the potential effects of Accutane with your doctor to make an informed decision on taking this medication.

Accutane Side Effects: Things To Look Out For

While it’s true that Accutane can cause side effects such as male hormone suppression, headaches, and pains in the muscles, these symptoms usually go away once you stop taking the drug. 

Some more serious side effects of Accutane treatment include liver and kidney disease, depression, pancreatitis, and blood clotting disorders. Getting your blood tested regularly and being on the lookout for unusual symptoms is an important step in preventing the development of serious complications.

Make sure to speak to your doctor immediately if during your treatment with Accutane you experience any of these symptoms:

• Unexplained bruising
• White of the eyes and skin has a yellow tone
• Difficulty urinating or blood in the urine
• Sudden changes in eyesight
• Severe stomach pain, and vomiting
• Severe headache that won’t go away
• Depression, anxiety, aggressiveness

Considering Other Treatment Options

We do know that some people experience a reduction in their T levels while taking Accutane and others do not, so it’s important that patients discuss their treatment options with their dermatologist before starting a treatment or making any decisions about their medical care.

If you have acne and want to take medications to treat the skin, consider using topical creams and serums, and having a daily skincare routine as advised by a dermatologist first. This is the safest bet to protect your hormones and overall health while controlling your skin breakouts. If those strategies do not work for you, your doctor will guide you through your Accutane treatment or any other medication that best suits your needs.

To Sum Up

Accutane is an effective acne treatment, but can temporarily result in lower testosterone levels in some patients to a certain extent. It’s important to know all potential side effects, especially if you have other health conditions like PCOS or thyroid dysfunction. If you still want to use this drug despite the associated risks, discuss the best ways to monitor your treatment with your doctor!

Key Takeaways

• Accutane is an effective acne treatment, but research has shown it can result in a significant decrease in total testosterone.
• Not every man on Accutane will experience a reduction in T-levels
• The effects of Accutane on male hormones are usually temporary and will resolve once you stop taking it
• Be on the lookout for symptoms of serious conditions that can develop during treatment with Accutane and discuss them with your doctor immediately
• Consider other skin treatment options before starting an Accutane treatment